Inclusion Criteria:
* Able to provide informed consent
* Female and male subjects over 35 years of age
* Has a desire for treatment with hyaluronic acid for skin depressions on both hands
* Must qualify to receive Juvéderm® VOLIFT®™ with Lidocaine as described in the current European Union Juvéderm® VOLIFT®™ with Lidocaine Directions For Use (DFU)
* Accepts the obligation not to receive any other hand cosmetic procedures or treatments at any time during the study (hand creams are permitted)
* Agrees not to change their normal hand care regimen throughout the course of the study.
* Women of childbearing potential must have a negative urine pregnancy test result at baseline (Day 1) and practice a reliable method of contraception throughout the study.
Exclusion Criteria:
* All contraindications as described in the current European Union Juvéderm® VOLIFT®™ with Lidocaine Directions For Use (DFU), as supplied with the product.
* Receiving or planning to receive anticoagulant therapy during the course of the study, or received anticoagulant within 10 days prior to study treatment and 3 days after.
* Receiving or is planning to receive anti-inflammatory drugs (oral/injectable corticosteroids or NSAIDs, e.g., aspirin, ibuprofen), or other substances known to increase coagulation time (vitamins or herbal supplements, e.g., Vitamin E, gingko) for 10 days prior to study treatment and 3 days after
* Undergone hand surgery, tissue grafting, or tissue augmentation with silicone, fat, or other permanent, or semi-permanent dermal fillers or be planning to undergo any of these procedures at any time during the study
* Undergone temporary hand dermal filler injections with any substance within 12 months prior to entry in the study
* Noticeable scarring, active inflammation, infection, cancerous or pre-cancerous lesion, or unhealed wound or have undergone radiation treatment in the area to be treated
* Subject with a dental infection (e.g. infected tooth or paradonitis) or have received dental cleaning within one month of such infection
* Subject with history of hypertrophic scarring on hands
* Any fibrosis or scarring or deformities on the hands - History of neurological disease that may affect peripheral neurological function
* Subjects with a history of Raynaud´s disease or phenomenon, or history of other disease that may affect peripheral circulation
* Subjects with a history of autoimmune disease or joint disease or connective tissue disease (e.g., rheumatoid arthritis, lupus, scleroderma etc.)
* Woman pregnant, lactating, or planning to become pregnant at any time during the study
* Received any investigational product within 30 days prior to study enrollment or be planning to participate in another investigation during the course of this study
* Subject with any skin disease (acute and/or chronic) on the treated zone, likely to interfere with the measured parameters or to put the subject to an undue risk.
* Subject with multiple allergies, anaphylactic shock history, evolutive allergic pathologies.
