A Study for Treatment of Partial Seizures in Children

Subject has diagnosis of partial seizures with/without secondary generalization, supported by: - Observed ictal events consistent with partial seizures with/without secondary generalization; Documented by reliable observers - 1 of following 3: - EEG at some time in past demonstrating focal abnormalities consistent with partial seizures - If the EEG is inconclusive or does not support partial seizures, then an MRI/CT will be done - If the MRI/CT fails to support a diagnosis of partial seizures, the subject may still qualify based on the principal Investigator's clinical diagnosis - Subject weighs at least 15 kg (33 lbs). - Parent/caregiver is able to keep an accurate seizure diary.

- Has had status epilepticus in the past 3 months prior to Screening - Has a history of any of: Cardiac (including clinically important abnormality on ECG); Renal; Psychiatric (including psychosurgery); Oncologic; Endocrine; Metabolic; Pancreatic; Hepatic disease (including clinical/serological history of hepatitis); Urea cycle disorder - Has: Expanding CNS neoplasm; Active CNS infection; Demyelinating disease; Degenerative neurological disease; Progressive encephalopathy; or any Progressive CNS disease - Has platelet count less than or equal to 100,000/mcL - Has blood chemistry ALT/AST value(s) greater than or equal to 2 times upper limit of normal at screening - Requires anticoagulant drug therapy - Receiving systemic chemotherapy - Requires treatment with aspirin - Subject is pregnant - Has been on ketogenic diet within 30 days prior to screening - Considered by investigator to be non-responder to valproate for treatment of epilepsy (e.g., Despite adequate trial with serum concentrations of 60 mcg/mL or greater, subject continues to have inadequate seizure control)