Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients

Study Identifier
M00-154
CT.gov Identifier
NCT00038220
EudraCT Identifier
Not available
EUCTIS ID
Not available
For general inquiries, please contact

844-663-3742 or [email protected]

Study Complete

Results Available

Scientific Result Summary
Available Language(s): English
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Study Details

Medical Condition
  • Human Immunodeficiency Virus (HIV)
    • Study Drug
  • Lopinavir/ritonavir
  • Efavirenz
  • Lamivudine
  • Tenofovir DF
    • Phase
    CSR.ORG
    Sex
    Female & Male
    Age
    18 - 65 Years
    Inclusion and Exclusion Criteria
    Inclusion Criteria:
    - Have HIV Infection. - Age 18 to 65 years old. - Show no signs of recent illness other than HIV infection. - Agree to use a barrier method of birth control during the study and for 30 days after study.
    Exclusion Criteria:
    - Are unable to follow study requirements (in the opinion of the investigator). - Are pregnant or breast-feeding. - Are unable to take medications by mouth. - Have chronic nausea or vomiting. - Have cancer other than Kaposi's sarcoma or basal cell carcinoma. - Have active, serious infections (other than HIV) requiring antibiotic injections within 15 days prior to screening. - Are taking any medications that are not allowed with ABT-378/r and efavirenz. - Are taking or have taken any other experimental drugs, antiretroviral drugs, or drugs that affect the immune system within 30 days of start of study without consent of the medical monitor. - Are receiving or have received radiation therapy within 30 days of start of study without consent of the medical monitor. - Have a history of drug abuse or mental illness that would prevent the patient from following the protocol requirements. - Have a history of kidney or bone disease.

    Protocol Summary

    The purpose of this study is to see if a novel 4-drug anti-HIV combination can suppress the

    growth of HIV in patients infected with the virus.

    Study Locations

    Location
    Status
    Location
    Aaron Diamond AIDS Research Center - Rockefeller University
    New York, New York, United States, 10021
    Status
    Not applicable